One day, a species of singing toilet-human hybrid creatures called the Skibidi Toilets mysteriously appear on Earth and start to invade the planet. Soon after their arrival, humans begin to vanish. A race of android figures called the Cameramen take up arms to defend Earth from the invading creatures, and an all-out-war ensues. Experts in technological innovation, the Cameramen develop a variety of weapons and become adept fighters, their greatest warrior being the colossal Titan Cameraman. Though, the Skibidi Toilets are also technologically advanced and have a giant fighter of their own: G-Toilet, their supreme leader. As the battle intensifies, a new race of androids with sonic powers called the Speakermen come to the Cameramen's aid, bringing their own Titan. The introduction of the Speakermen marks the formation of The Alliance, a coalition united in their purpose of defeating the Skibidi Toilets. Eventually, a third faction of androids, the TV Men, join The Alliance, contributing yet another Titan and a new set of abilities, including hypnosis and teleportation. As the war progresses, new variants of Alliance members and Skibidi Toilets emerge, each side becoming increasingly stronger through technological advancement. After many episodes without seeing humans, a man known as the Secret Agent starts to make appearances. Though his motives remain a mystery, he seems to work in favor of The Alliance, supplying them with tools to fight the Skibidi Toilets. Later, a new, powerful race of Skibidi Toilets called the Astro Toilets enters the narrative who have a contentious relationship with G-Toilet. Throughout the series, amid the chaos of war, characters form deep bonds, face betrayals, and experience poignant moments of sacrifice and heroism.