400,000 Chromosomes Ago

“ Wh-Why do I even hang out with you guys? ”
Chin-Chin
The Dark lord that monolithically reigns over Frank and his realms, Chin-Chin is both his deity and graven image. Frank both respects and fears Chin-Chin.

After the death of Dade, Frank came to resent and outright insult Chin-Chin, referring to him as a "stupid poopy face". But, being a caring god and understanding that Frank was distraught, Chin-Chin allowed him to do so.

Dade
Proud father and beloved friend, Dade, Chin-Chin rest his soul, was Frank's father and only named parent. Frank seemed to be confused when around him, as he once called him "Bald Man" instead of father.

Pink Guy
One of his greatest friends, acquaintances, fellow musicians, and in some cases minion, Pink Guy is Frank's go-to guy. Together for an uncountable number of chromosomes, the pair have had many journeys, suffered much tragedy, and experienced many wonders.

When Pink Guy has seizures or extreme fits of masturbation, Frank finds it to be "pretty funny", and even tries to safeguard him from Jamal by stating that Pink Guy "is just trying to express himself."

Prometheus
“ Those are some nice muscles, mane. ”
A man of exquisite physique. When he and Frank are in the same area, Prometheus becomes the alpha male and dominates the situation. He takes offense during the Batsu Games when Frank compliments his musculature, striking him with slaps.

Red ♥♥♥♥
Another good friend of Frank's, with whom he has shared many autistic experiences. Thought to be Papa Franku's second right hand mean, since Franku may indeed have two right hands.

Sometimes, Red ♥♥♥♥ can be seen guarding over Frank when he is in hiding, as he did so silently when Frank was late with Chin-Chin's 2015 Sacrifices

Safari Man
A strictly platonic, middle ground relationship is shared between these two individuals. A random squatter who stays in his home, Safari Man is usually uncaring and apathetic to Frank when he is in a bad situation, and is extremely selfish and hides at any immediate signs of threat. Frank even describes him as an ♥♥♥♥♥♥♥.

During the Japanese 101 segments, Safari Man seems to be more knowledgeable about the language than Frank, and even denounces his attempts at questioning his phrases.

Salamander Man
Salamander Man is also a devout minion of Frank, and is usually the scout who warns Frank of impeding danger or threats. Frank regards Salamander Man as a great musician and has even rescued him from Chin Chin.

Tit Job Specialist
A crazy basketcase who is hyper-sexually aroused and possibly masochistic, TJS is ???