SEELE (ゼーレ) was a mysterious group of beings shown in Rebuild of Evangelion to have significant influence over NERV.

SEELE strive to accomplish the Human Instrumentality Project - the goal of uniting the human race as one, thus ending all the wars and individual struggles of mankind. The Seed of Adam (the progenitor of the angels) was the original seed to arrive to Earth, but because of the arrival of the Seed of Lilith (the progenitor of humanity), Adam's seed was inactivated, so SEELE views Humanity as the false successors of Earth, and the Angels as the true successors, the sons of God, and for that Humanity is burdened by the "Original Sin" because it should never have existed. They work to destroy the Angels, then unite all humanity as one and sequentially unite with Lilith and Adam, so that they can become part of God—the next stage of existence.