I can figure out most of them, but I can't figure out what SHO is short for. VIT - Vitality AGI - Agility DEX - Dexterity INT - Intellect/Intelligence MEL - Melee SHO - ? OPE - Operations (from another thread answer, not sure exactly what this does) GUA - Guard...

Using Red's skill "Increase Output" says "Modified Vacuum/Mechanical Weapon/Drone is not equipped!" and seems to do nothing when he is equipped with either Small Chainsaw or Electric Nailbat (both Mechanical Weapons).

I know the tags are from the community, but from the description (I didn't play it) I would assume (and hope) that this isn't a roguelike. Is this right? Thanks in advance for a response!

Is this different from the first game?

I like to play games in chronological order, except if the sequel is way too far in the future (in-lore) and there is not much reference to the games before it.