To become one with your inner laziness, press X and then Shift and enjoy the nice run around New York.

You can also hold ctrl when running at an object you want to climb to automatically climb it when in range!
(Thank you Bill Cipher!)

Alternatively, you can turn on parkour mode in the settings and you will vault over anything while running without pressing control!
(Thank you undead indigo!)

If you think you want to get a season pass for this game, please do. Season pass holders get monthly rewards (which I don't see as super fair but whateva) so buy it if you think this game will hold you over for a while and want a cheaper price for all the DLC!

One of the most useful things in this game is the ability to switch your line of sight, while aiming press shift to take on a new perspective of the battlefield by switching your sights left and right, sometimes this will help you out killing enemies who are around corners on the other side of your gun.

If there are enemies closing in on you and you cannot heal, try firing without aiming, it is less accurate but way more safe.

You can also hit Tab or Middle Mouse to zoom in if your weapon has a scope! (Thanks Xiko)

To use a consumable, such as water (20% more dmg to elite enemies) hold down your quick medkit button, there are quite a few and don't be afraid to use them, they are life savers sometimes.

You can also select special grenades, such as the flashbang or tear gas by holding down the grenade button and selecting that grenade by moving your mouse.
(Thank you to noMad for reminding me to put this in!)

Cleaners: For cleaners my tip is to shoot the fire container on their back, it sends them into a panic as they start to explode, dealing heavy amounts of damage to them and other enemies close to them.

Some special enemies have weakpoints similar to the Cleaners' fuel tanks. Grenade guys have a pouch on them somewhere that explodes when taking enough damage (Rioters on their back, Cleaners on their left hip) and LMG guys have ammo packs on their backs that'll send bullets flying everywhere.

Keep in mind that it doesn't guarantee an instakill to shoot those weakpoints, especially on purple or gold ranked enemies, but it will still do considerable damage and, at least for the duration of the Panic animation, take 'em out of the fight.
(Thank you Zeph Sunstrider!)

This game is by Ubisoft, meaning if you press Shift + F2, you open the UI where you can unlock items with points gained by doing achievements.

I will update this guide as I figure out more neat tricks and go through the game at my own pace, I will however take suggestions, feel free to comment your tips! (I will credit you don't worry)