So, we need to change the parameters of the Config.ini file. Find this file in this path:
C:/Users/USER(name of your entry in Windows)/AppData/Local/CAPCOM/DEVILMAYCRY4SPECIALEDITION/Config.ini
Or use the application search by typing %LocalAppData%.
We found this file, now we need to copy the text below and paste it into this ini file: (Pre-deploy this ini file to the desktop)
[DISPLAY]
Resolution=1920x1080
Aspect=DEFAULT
RefreshRate=60.00Hz
FullScreen=ON
VSYNC=ON
[JOYPAD]
ProductName=Generic USB Joystick
A=2
B=1
X=3
Y=0
LEFT=15
RIGHT=13
UP=12
DOWN=14
START=9
BACK=8
LT=4
LB=6
RT=5
RB=7
LSTICK_PUSH=10
LSTICK_VERT=Y
LSTICK_HORZ=X
RSTICK_PUSH=11
RSTICK_VERT=Z
RSTICK_HORZ=RZ
[GAME]
MouseBaseSpeed=2.000000
[GRAPHICS]
HDR=DEFAULT
AntiAlias=MSAA8X
AltAntiAlias=NONE
DeferredLightingLight=APPROXIMATE_SPECULAR
DeferredLightingHDR=INTEGER_LOG
SLI=ON
GodRay=ON
Stereo=OFF
EffectVolume=HIGH
TextureResolution=2
quality=2
framerate=2
TextureDetail=HIGHEST
TextureMipLimit=2
[CPU]
JobThread=2
RenderingThread=ON
[window]
MainX=0
MainY=0
After that, save the file and go into the game. Now the friezes should disappear, but I do not guarantee that after that you will not stop lagging in open places.
It helped me personally, I hope it helps you too.

I hope it helped you and that's where I say goodbye to you.
This manual was first created by me into Russian, but I decided to translate it into English so that everyone could read this manual.