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Just from memory, I can say that in zones in which you cannot return to such as Dreadnought Leviathan; all the "One Time Only" chests that contain spells and what not have a linked chest elsewhere. So you can't even miss those. While these zones do have "One Time Only" chests that you can miss, they generally contain consumable items like Reflectaga Motes and the link. Nothing too dramatic.
Bottom line here is; don't worry about "Missing Out" on chests, as it's highly unlikely you will ever miss anything important. Just follow the guide if you’re worried about it and make sure you snag all the "One Time Only" chests in each zone as you progress.
Also, don't worry about asking too many questions if you don't fully understand it. That's what we're all here for bud.