The eardrum, or tympanic membrane, is a thin, cone-shaped membrane that separates the external ear from the middle ear in humans and other tetrapods. Its function is to transmit sound from the air to the ossicles inside the middle ear, and then to the oval window in the fluid-filled cochlea. Hence, it ultimately converts and amplifies vibration in air to vibration in fluid. The malleus bone bridges the gap between the eardrum and the other ossicles.[1]

There are two general regions of the tympanic membrane: the pars flaccida (upper region, see picture on right) and the pars tensa. The pars flaccida consists of two layers, is relatively fragile, and is associated with eustachian tube dysfunction and cholesteatomas. The larger pars tensa region consists of three layers: skin, fibrous tissue, and mucosa. It is comparatively robust, and is the region most commonly associated with perforations.[2]

Rupture or perforation of the eardrum can lead to conductive hearing loss. Collapse or retraction of the eardrum can also cause conductive hearing loss or even cholesteatoma.