After being given the mission to ambush any fleeing ghouls and neutralize the One-Eyed Owl, he was stationed within the underground Route V14, where he encountered and single-handedly killed dozens of ghouls. Upon having his gaze fall on Ken Kaneki, he quickly approached him with the intention of completing his mission and, without warning, dealt an attack towards Kaneki that tore a large chunk out of his abdomen. Before Kaneki could recover and fight, he lunged his quinque IXA through the back of Kaneki's skull, which pierced his brain and destroyed his left eye. He easily dodged Kaneki's rapid kagune strikes and witnessed a sudden emotional outburst from Kaneki, during which Kaneki recited a Hakushū poem. Apparently moved by the poem, he made note of Kaneki's identity, then offhandedly mentioned that he could tell it was raining outside from the sound of water pouring in from above. He stated that his sense of time got dulled when he was underground. Then brought out his other quinque, Narukami, and activated it. He declared that his objective was to ensure no ghouls would pass through Route V14, and released bolts of Rc projectiles towards Kaneki. After Kaneki dodged those attacks, he commanded his quinque to go into remote activation and continued to strike at Kaneki, keeping the manic ghoul at bay. He blocked a desperate attack from Kaneki's kagune using IXA's defensive barrier, but was surprised that Kaneki's blow managed to break the barrier, and so complimented his opponent. He went on to impale Kaneki through the abdomen with IXA, lifted him high into the air briefly before he threw him back to the ground. He stated that he had not expected Kaneki to damage his quinque and finished Kaneki off with a stab through the other eye and mentioned that he needed a new quinque. He noticed a bleeding scratch on his right cheek. Later on, he confronted the One-Eyed Owl alone and managed to sever its arm, forcing it to escape and mirrored his battle with the first Owl years ago. Later it was revealed that their battle was only a performance and in reality he let Eto escape with Yoshimura as a part of their plan. After the CCG imprisoned Kaneki in Cochlea, he visited Kaneki in order to observe him. During one such visit, he witnessed an emotional outburst by Kaneki, now called Prisoner #240. As Kaneki frantically begged to be let out to save his friends, he calmly told Kaneki that he had killed all of them. He inquired about the amnesiac Prisoner #240's state with the Warden Shinme Haisaki. Haisaki told him that Prisoner #240 was refusing food, was apparently tormented by nightmares that made him cry worse than a baby during the night, and picked at his eyes so much they were festering; thus, the Warden expected the prisoner to die soon due to starvation. Thereafter, he started to bring Prisoner #240 books to read, and Prisoner #240's health improved substantially. Some time after the Owl Suppression Operation, he along with Akira Mado were in charge of supervising Haise Sasaki and his Quinx members. Following the failed operation to capture Torso and Serpent, he summoned Haise to an S3 meeting. He did a minor spat with Haise, subsequently returned the book he borrowed from Haise to him. When Sasaki apologized for using his kagune to fight Serpent, he dismissed this apology, and listened attentively as Haise compared him, Akira and the rest of the Quinx Squad to a somewhat dysfunctional family.