Annihilation is a 2018 science fiction psychological horror film written and directed by Alex Garland, based on the 2014 novel of the same name by Jeff VanderMeer. It stars Natalie Portman, Jennifer Jason Leigh, Gina Rodriguez, Tessa Thompson, Tuva Novotny, and Oscar Isaac. The story follows a group of explorers who enter "The Shimmer", a mysterious quarantined zone of mutating plants and animals caused by an alien presence.

Annihilation was released theatrically in the United States by Paramount Pictures on February 23, 2018, and in China on April 13, 2018.[6] It was released digitally by Netflix in a number of other countries on March 12, 2018. It received positive reviews from critics and audience. It grossed $43 million worldwide. According to Empire magazine, the film addresses "depression, grief, and the human propensity for self-destruction".[7]